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First, SARS-CoV-2 is able to mutate often, and is unlikely to be eradicated in the near future, creating a need for booster shots

Long-term exposure of quiescent human fibroblasts to IGF-1 reduced viability and increased senescent cells, associated with reduced autophagy and dysfunctional mitochondria

Proc Natl Acad Sci USA, 92, 43374341

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