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These findings support the theory that high-fat diets (potentially causing insulin resistance and T2DM) hinder mitochondrial biogenesis, which could clarify the development of anomalous myocardial performance in cases of obesity, insulin resistance, and fully developed diabetes [153]
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Research has also found that theobromine has differential contributions to mood and cognitive function compared to caffeine, providing further insight into the distinct yet synergistic nature of these naturally occurring stimulants [29]
Caspian J Environmen Sci 22(4):841847 Ashkani-Esfahani S, Bagheri F, Emami Y, Esmaeilzadeh E, Azarpira N, Hassanabadi N, Keshtkar M, Farjam M, Koohi-Hosseinabadi O, Noorafshan A (2016) Protective effects of co-enzyme Q10 on thioacetamide-induced acute liver damage and its correlation with behavioral, biochemical, and pathological factors
