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Description
Are toxic biometals destroying your childrens future

Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2), a bifunctional enzyme with methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase activities, provides one-carbon units for purine biosynthesis

Since sulfonium compounds are high-energy compounds, a -elimination reaction yielding THT and aminoacrylate should be energetically favorable
2011;342:d2218
