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The 1.5 g carnitine dose increased the urinary GBB concentration from a median of 1.4 M (IQR: 0.661.73) to a median of 10.3 M (IQR: 5.723.5) at 24 h postintake, with the level remaining elevated even at 48 h (Figure 5C)

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doi: 10.3389/fcvm.2023.1128195 Received 20 December 2022 Accepted 11 May 2023 Published 02 June 2023 Volume 10 - 2023 Edited by Marco Zanobini, Monzino Cardiology Center (IRCCS), Italy Reviewed by Anik Ilona Nagy, Semmelweis University, Hungary Valentina Mantegazza, Monzino Cardiology Center (IRCCS), Italy Updates Copyright 2023 Ronco, Buttiglione, Garatti and Parolari

The dropout rate was low (only 6 participants didnt finish the study), indicating the study was carefully conducted and had few severe side effects