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It also induces metabolic remodeling, promotes glutamine synthesis, and inhibits the production of pro-inflammatory chemokines, effectively aiding in weight loss (181)

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It is possible that these acetylation marks also help to promote chromatin relaxation or other DNA damage pathways, which will be investigated in future studies

Nevertheless, therapeutic hypothermia is only partially effective (5760), and many infants with HIE remain at substantial risk of death or severe long-term neurodevelopmental impairments (55)