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Indeed, loss of function due to mislocalization of TDP-43 causes aberrant cryptic splicing in genes including STMN2 and UNC13A that drive the progression of ALS[1215, 17]

Moreover, the mitochondrial calcium uniporter (MCU) increases mitochondrial ROS (mROS), activating the Keap1-Nrf2 antioxidant response and upregulating SLC7A11, which enhances cystine uptake and inhibits ferroptosis in PDAC [113]

Khi apply, da nhanh chng cm nhn c s mt du, thoi mi cho da
doi: 10.1046/j.1523-1755.2002.00600.x
