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ATPase activity assays confirmed that coumarin stimulates ATP hydrolysis by P-glycoprotein (P-gp), indicating that coumarin acts as a substrate for it, and the nanoparticles were shown to inhibit P-gp-mediated efflux, enhancing drug retention in cells

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Associations of anaemia and iron deficiency with health-related quality of life in patients with chronic kidney disease stage G3b-5 in japan: Sub analysis of the Reach-J CKD cohort study