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Results: Prescription type was associated with all four side effects (all p 0.88), indicating that younger patients reported higher frequency of poor appetite and end-of-dose crash, and lower levels of insomnia

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Despite its theoretical appeal for treating insomnia ( Dopamine plays a crucial role in the transition from nonrapid eye movement (NREM) sleep to rapid eye movement (REM) sleep through a transient increase in the basolateral amygdala (BLA), acting on D2 dopamine receptors to initiate the NREM-to-REM shift

Opioid system and human emotions