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Description
In hypoxic conditions, HIF-1 acts as the main mediator of a series of in vivo pathophysiological responses, including angiogenesis, cell proliferation, and transcriptional induction of survival genes (31)

doi: 10.1111/apha.12086

This process is defined as active immunotherapy as the hosts immune system is either de novo activated or restimulated to mount an effective, tumor-specific immune reaction that may ultimately lead to tu-mor regression

It helps with metabolism, fat burn, weight loss, anxiety energy and sleep
