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Compared to the WT USP2, USP2 K447R transfection suppressed TGF1-mediated upregulation of USP2 lactylation, which was not further affected by SIRT2 OE (Fig
Taking evidence in account, more studies are necessary to go deep into the participation of oxidative stress, mitochondrial dysfunction and inflammatory response in the development of PDN
The correlations between S-5-HT and fatigue were also similar
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