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Distinguishing medication effects from psychological responses to dietary restriction and body changes is challenging

Some people reject therapies studied in large populations while accepting compounds with little or no human data

Finally, from a general point of view, the consistent effect of NSAIDs (24, 25), and thereby, the consistent NSAIDs effects on sphincters failure in rat, and vice versa, the consistent sphincter failure related to NSAIDs, thus, a commonality for both NSAIDs and sphincter failure, could be hardly combined with the quite inconsistent effects of NSAIDs on sphincter pressure in different species so far reported (17-23)

These substances pose serious health risks and are completely unacceptable in consumer inhalation products