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The two-layer membrane divides mitochondria into multiple cavities, which is known as mitochondrial compartmentalized structure. The mitochondrial structure mainly includes four distinct regions, including mitochondrial outer membrane (Outer Mitochondrial MembraneOMM), mitochondrial inner membrane (Inner Mitochondrial MembraneIMM), mitochondrial matrix, and intermembrane space (Kramer and Bressan, 2018)

Use with caution in patients with hormone-sensitive tumors or cancers

This indicates that hypoxia severely impairs the efficiency of mitochondrial energy production

Maintain cold-chain integrity whenever possible