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All this evidence indicated that active transporter on the abluminal side triggers the release of Glu from cerebrospinal fluid (CSF) into ECs and, concomitantly, facilitative carriers on the luminal membrane mediate Glu efflux from ECs to plasma ( Regarding the specific facilitative transporters for Glu on the luminal side, there are two plausible candidates

The recent demonstration of the importance of oxidative stress in osteoarthritis places the use of intra-articular antioxidants, namely glutathione and its precursor, as an important interventional strategy for both joint preparation for biologic therapies as well as a powerful ally in viscosupplementation