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Li Z.S., Lu Y.P., Zhen R.G., Szczypka M., Thiele D.J., and Rea P.A
conducted a CRISPR/Cas9 genetic screen with KEAP1 -mutant lung cancer cells and found that NRF2-addicted cancer cells are highly dependent on glutamine uptake, and that, consequently, inhibition of glutamine-derived glutamate by glutaminase inhibition effectively suppresses NRF2-addicted lung cancers (Romero et al
Levels greater than 3.7 mg/dL at 4872 hours post-ingestion have been reported as associated with higher mortality from acute liver failure
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