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Tumor Angiogenesis and Anti-angiogenic Strategies for Cancer Treatment
In colorectal cancer models, the combination of CB-839 and cetuximab significantly inhibited cell proliferation and increased apoptosis and necrosis, accompanied by decreased levels of the mTOR signaling target pS6, resulting in delayed tumor growth
[DOI] [PMC free article] [PubMed] [Google Scholar] Eichel K, von Zastrow M
Getting this right is fundamental
