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It works best with physical activity, as it helps convert fat into energy

Mannitol to prevent cisplatin-induced nephrotoxicity in patients with squamous cell cancer of the head and neck (SCCHN) receiving concurrent therapy

doi: 10.1016/j.freeradbiomed.2014.07.034

Past studies have shown that CR decreases ROS production (via reducing NADH levels), thus minimizing oxidative damage and extending the lifespan [164]
