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The increased activity of -secretases and concurrent reduction in the activity of -secretase may partially explain why melatonin treatment results in diminished A levels in the brains of both sporadic and transgenic animal models of AD [55,56,57]
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J Clin Endocrinol Metab 87: 489-499 Saravanan P, Chau WF, Roberts N, Vedhara K, Greenwood R, et al
