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10.3390/cancers15194728 72 ChristianC
Edited by Professor Massimiliano Agostini Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made
Harness 2010:371-383

The medication is typically initiated at a lower dose and gradually titrated upward to minimize gastrointestinal side effects and optimize therapeutic benefit
