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[75] Simpson, David M

Certain MNs can increase mitochondrial antioxidant capacity and mitigate oxidative stress-induced damage

These effects typically emerge during dose initiation or escalation and often diminish over time as the body adjusts to the medication

Although many of these studies have based their findings on peripheral markers of abnormal metabolism, many studies have documented some of these same abnormalities in the brain of individuals with ASD, including mitochondrial dysfunction and oxidative stress (30) and one study has demonstrated a link between oxidative stress, inflammation, and mitochondrial dysfunction in the brain of individuals with ASD (23)