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Next, the binding kinetics and affinity at pH 5.5 were determined using SPR, as before, where the GLP-1 albumin fusions were injected over biotinylated human FcRn immobilized on an SA sensor chip (Fig

In the adult liver, LSECs exhibit distinct zonal markers 54 , which was recreated in the organoids where the endothelial structures acquire increasing CD54 + expression in proximity to the hepatocyte layer, which suggests that endothelial cell specialization is potentially a product of the niche (Fig

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