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Additionally, BPC-157 upregulates several important growth factors, including epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), and fibroblast growth factor 2 (FGF2)

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The peptide influences laminin-5 (LN-5) expression in a temporally sophisticated mannerinitially inhibiting LN-5 to promote cellular proliferation and differentiation, then upregulating LN-5 expression during middle and late healing stages to improve the matrix environment and promote epidermal cell migration
