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Ou et al., 2021)

A great deal of work in both rodents and humans highlights the nucleus accumbens (NuAc) - a main component of the ventral striatum- as a critical node of the brains reward and motivation circuitries 9,1114
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Excessive shortening triggers persistent DNA damage response or genomic instability, causing cellular senescence, and is also strongly linked to lifespan (Whittemore et al., 2019

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