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In the early endosomes, internalized GPCRs undergo dephosphorylation by protein phosphatase 2A (PP2A) to be recycled back to the plasma membrane, where they become ready to be activated and respond to a new wave of stimuli (Gupta et al., 2018

Cell volumetry The volumes of A549 and U87-MG cells were measured using a Multisizer 4 (Beckman Coulter) with a 100 m aperture tube