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Furthermore, apoptosis can be attenuated by inhibiting ferroptosis since it lowers the production of pro-apoptotic proteins ( The necrosome, a complex made up of receptor-interacting protein kinase (RIPK) 1 and RIPK3, is responsible for regulating necrosis, or necroptosis ( Inflammasome activation causes pro-inflammatory cytokines, including IL-1 and IL-18 to be released during pyroptosis, a type of programmed cell death

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Network similarity and prediction algorithms involve topological similarity analysis, node similarity-based network analysis, and prediction algorithms based on machine learning or network topology, which can be used to infer drug-target interactions or screen potential drugs (Vella et al., 2018)

(Beijing, China) were used for experiments