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In Botswana: Current status and potential for commercialization

Clonality of select AML driver mutations estimated as cancer cell fraction (CCF, n = 173 patients)

suggests that a key element in this process involves the activation of G-proteins, which are closely associated with the inner surface of the cell membrane and activate downstream pathways leading to the production of secondary messengers such as cyclic adenosine monophosphate (cAMP) and inositol triphosphate (IP3)

Agunwa, I
