nrf2 glutathione peroxidase pathway in wound healing. ARE – antioxidant response elements; FGF Frontiers | Nrf2 and Ferroptosis:

Among them, organic anion transporter 1 (OAT1) and organic anion transporter 3 (OAT3) are responsible for recognizing organic acids such as methotrexate and nonsteroidal anti-inflammatory drugs, while organic cation transporter 2 (OCT2) mediates the excretion of organic bases such as metformin and cimetidine (Wang C

BiomarkerDriven Clinical Trials and Nanoformulations Wellcharacterized polyphenols such as curcumin, EGCG, and resveratrol have shown remarkable preclinical promise but have produced inconsistent clinical results

10.1038/srep35659 102 KantamneniS

Although the current therapeutic practices have significant variability in routes and dosage regimens, we concluded that management of IGS predominantly centers on lifelong Vitamin B12 supplementation, which is sufficient for preventing hematological and neurological abnormalities associated with this disorder