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What the Clinical Evidence Actually Shows This is where the conversation has to get more careful

Most researchers see two to four pounds of initial weight loss, with some of that being water weight as insulin sensitivity begins improving

This occurs by the activation of signal transduction pathways involved in the control of transcription of GCLC and GCLM genes but also there is some evidence of mRNA stabilization by oxidants and electrophiles (Liu et al., 1998)

Excessive Fe 2+ impairs the function of pancreatic cells and liver cells through oxidative stress and mitochondrial injury, leading to insulin resistance and affecting NAFLD development ( 2+ , elevates ROS levels, and leads to ferroptosis ( in vitro and in vivo ( Intervention effects of herbs or herbal extracts in regulating ferroptosis on non-alcoholic fatty liver disease Currently, there is no agreed standard or definitive effective drugs for the treatment of NAFLD