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6 Metallomics and omics synergies in the study of metal mixture effects on human disease pathways The emerging fields of metallomics and the metallome represent powerful frameworks for understanding the complex biological effects of metal exposures, particularly in the context of environmental co-exposures

A foundational pilot study demonstrated that following oral administration of a broccoli sprout preparation, sulforaphane metabolites are delivered to and can be measured in human breast tissue, providing critical proof-of-concept for its direct bioactivity in the target organ (99)

HR+, HER2- Advanced breast cancer and CDK4/6 inhibitors: mode of action, clinical activity, and safety profiles

Quartararo LG, Vaccaro A.R., Carbone JJ