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The rate parameters of biochemical interactions ( Materials & Methods: R1 -R12 ) describing the basic life cycle model are obtained through a systematic strategy described here: 1) following rate constants were obtained from literature: 1) half-time of PDK1-mediated phosphorylation event of nascent, endogenous PKC enzyme in COS-7 cells at activation loop (Supplementary Materials 2 Table S1)
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They are the major carriers of endogenous (hepatic-derived) triglycerides and transfer triglycerides from the liver to peripheral tissue mostly during the fasting state for energy utilization and storage
