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Because individuals with CC have aberrantly low amounts of LC in muscle tissue, mitochondrial -oxidation of long-chain fatty acids does not proceed proficiently (Szefel et al., 2012)

MDA, an aldehyde with reactive properties formed through the peroxidation of polyunsaturated fatty acids, serves as a prominent OSM in IBD, reflecting lipid peroxidation and cellular damage and functions as a marker for cellular damage caused by free radicals (174)
