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Activating mutations of phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha (PIK3CA) gene confer sensitivity to PD-L1 checkpoint inhibition in metastatic adenocarcinoma patients

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79 The release of mature IL-1 and IL-18 amplifies the inflammatory response in the liver, leading to the recruitment and activation of immune cells, including neutrophils, monocytes, and macrophages

The arteries were then isolated from the sacrificed mice and imaged using the IVIS imaging system to visualize the distribution of the NPs