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The cleavage of Snitrosyl group can occur spontaneously in the case of exposure to reducing agents (ascorbate, GSH), metal ions (Cu 2+ ), UV radiation, ROS, or nucleophiles [12] or can be catalyzed by denitrosylases that remove the nitrosyl group from Snitrosothiols

Thus, an overview of sustained-release DDSs and permeable DDSs, with a particular focus on polymeric nanoparticles used for IA injections

This review identifies overlapping genetic variants and epigenetic mechanisms that contribute to both conditions, highlighting the potential for integrated therapeutic strategies and personalized medicine approaches to improve outcomes for individuals at high risk

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