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Fe 3+ is reduced to Fe 2+ by the six-transmembrane epithelial antigen of prostate 3, which is stored in the ferritin heavy chain (FTH) and ferritin light chain (FTL) ( 2+ is stored in ferritin (Fn) and becomes a part of the labile iron pool, which plays a dominant role in ferroptosis

A major role of the endocytic pathway is the degradation or recycling of cell surface receptors in fact, a lot of this pathway was worked out through the study of the LDL receptor

As a result, the C-2 proton is readily abstracted, generating a carbanion

[DOI] [PMC free article] [PubMed] [Google Scholar] Perez-Aso M, Segura V, Mont F, Barettino D, Noguera MA, Milligan G, DOcon P