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Jutkiewicz EM, Kaminsky ST, Rice KC, Traynor JR, Woods JH: Differential behavioral tolerance to the delta-opioid agonist snc80 ([(+)-4-[(alphar)-alpha-[(2s,5r)-2,5-dimethyl-4-(2-propenyl)-1-piperazinyl ]-(3-methoxyphenyl)methyl]-n, n-diethylbenzamide) in sprague-dawley rats

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Acute respiratory failure induced by magnesium replacement in a 62-year-old woman with myasthenia gravis

When safety of the study participants and technological developments allow, so called biomarkers can be used to collect PD data to understand if the drug reaches the target, binds to the target and exerts its expected pharmacological activity within the dose range tested