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Furthermore, risk of deficiencies of key nutrients that are essential cofactors, such as folate and B12, for methylation and conversion of homocysteine may increase in prevalence postmenopausally, in response to disruptions to oestrogen levels (Vasquez-Lorenete et al., 2022)

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Cellular effects duration vs plasma half-life Critical distinction: Plasma half-life duration of effects GHK-Cu clears blood in hours But cellular effects last days How GHK-Cu works: Peptide binds to cell surface receptors Triggers intracellular signaling cascades Activates gene expression changes Initiates collagen synthesis, wound healing, etc
