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Year 2014 Mechanisms underlying the antihypertensive effects of garlic bioactives Conclusions Although a myriad of mechanisms have been proposed to explain the effect of garlic and its bioactive constituents in mitigating hypertension, there is still limited understanding about the specific molecular and biochemical pathways involved

severe or persistent upper abdominal pain should prompt urgent medical assessment [10] [11] Dehydration and acute kidney injury (AKI): gastrointestinal fluid losses can lead to dehydration, which may precipitate AKI, particularly in those with pre-existing renal impairment or those taking nephrotoxic medicines Delayed gastric emptying: this may affect the absorption of orally administered medicines, including contraceptive pills and thyroid replacement therapy [11] Injection site reactions: redness, bruising, or discomfort at the subcutaneous injection site Heart rate changes: increases in resting heart rate have been noted with GLP-1 class agents [14] [15] Hypoglycaemia: particularly if used alongside insulin or sulphonylureas Potential pancreatitis risk: a class concern with GLP-1 receptor agonists

Biochem Biophys Res Commun (2003) 304:30812
