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TMPRSS2 expression dictates the entry route used by SARS-CoV-2 to infect host cells

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Cell Stem Cell 31 , 11011112 (2024)

In mouse models of ASCVD (e.g., LDLR -/- ), a high-fat diet expands bone marrow progenitors and promotes myelopoiesis, accompanied by long-term epigenetic changes linked to NLRP3 inflammasome activation and increased IL-1 secretion