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Critically, opioids are contraindicated in the longterm management of nociplastic pain due to a profound lack of analgesic efficacy, coupled with a high risk of inducing opioidinduced hyperalgesia, physical dependence, respiratory depression, and overdose [402]
Veldhuis JD, Keenan DM, Bailey JN, et al
Copper Peptide: The collagen amplifier
[DOI] [Google Scholar] 169.Majumder A., Sheth F., Patel M., Doshi B., Shah N., Thankor P., Vaidya R., Sheth J
