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Haemochromatosis presenting as congestive cardiomyopathy and responding to venesection
In clinical trials, Retatrutide was associated with a greater increase in resting heart rate than Tirzepatide

This mechanistic diversity strengthens the growing recognition that treatment strategies extending beyond the CNS, particularly those involving the gut microbiota or peripheral metabolic pathways, may offer complementary therapeutic benefits

doi: 10.1136/gutjnl-2018-318126 30 KalisperatiPSpanouEPaterasISKorkolopoulouPVarvarigouAKaravokyrosIet al
