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Prescribing an unapproved new drug outside a trial is technically illegal under the FDCA (aside from narrow compassionate-use exceptions)
Studies on the living cornea in vitro

Allometric scaling to humans is not validated, and no published human dose exists
[DOI] [PMC free article] [PubMed] [Google Scholar] Rajan 2002 Rajan S, Wallace JI, Beresford SA, Brodkin KI, Allen RA, Stabler SP
