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Now, this is where it gets interesting for future research
312 As the endosome matures and pH decreases, ASGPR dissociates from the GalNAc conjugate and recycles back to the hepatocyte surface
However, Galloway and McLellan found that while an AP-1 site at 340 of human GCLM modulated basal expression of GCLM, neither the AP-1 site nor the ARE/EpRE site at 302 was involved in mediating the up-regulation of GCLM by TBH (Galloway et al., 1998)
