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Hepatoprotective effects of berberine on acetaminophen-induced hepatotoxicity in mice

Hrd1 can recognize and bind NRF2, directing it to the ERAD pathway for ubiquitination and proteasomal degradation [55]
This bypasses the energy-intensive de novo synthesis pathway
Free T4 and T3: free T4 is typically low in hypothyroidism and elevated in hyperthyroidism
