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[22] Specificity is also an important aspect of CAMKII signaling involving nanodomain calcium

It inserts into the membrane, disrupts its integrity, and triggers the release of cytochrome c and other pro-apoptotic factors

Int J Biol Sci

Burnett AL, Aus G, Canby-Hagino ED, Cookson MS, DAmico AV, Dmochowski RR, et al