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Ablation of ferroptosis inhibitor glutathione peroxidase 4 in neurons results in rapid motor neuron degeneration and paralysis

The upregulated expression of Piezo1 is associated with edema (Krivoshein et al., 2022)
The choice between medications should rest primarily on efficacy data, tolerability, availability, and cost rather than the B12 inclusion, which is valuable in both formulations

Lyon C, Langner S
