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Wise RA, Holbrook JT, Criner G et al

The deterioration of the physiological structure in various disorders and the physiochemical properties of NDDS can enable the passive accumulation of NDDS in the tissues [111]

Astaxanthin protects astrocytes against trauma-induced apoptosis through inhibition of NKCC1 expression via the NF-kappaB signaling pathway

25, 38 As aberrations in the TP53 gene and t(4:14) translocations are seen in 15% of patients 49 and correlated with short progression-free survival and resistance to alkylating agents at relapse, 50 the ability of BSO to sensitize MM cells with this phenotype suggests that BSO+L-PAM may have clinical activity in the most aggressive forms of MM