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Formulations of cyanocobalamin injection containing benzyl alcohol as a preservative should also be avoided in premature neonates and those with hypersensitivity due to its association with gasping syndrome (10-12)

16 In this study, where the children were supplemented daily with two recommended daily allowances (RDA) for 6 months, the effect of vitamin B 12 supplementation was more apparent in children who had evidence of vitamin B 12 deficiency at the start of the study

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Signs include: Hives or widespread rash beyond the injection site Swelling of face, lips, tongue, or throat Difficulty breathing or wheezing Rapid heartbeat Feeling faint or losing consciousness These symptoms require immediate medical attention