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The premise is not fully settled: No endogenous MGF peptide has been isolated in vivo, and synthetic MGFs effects differ from known IGF-1 products so claims about its physiological role should be read with genuine caution [1]

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Nature 375:599603 Farber K, Kettenmann H (2005) Physiology of microglial cells

Ferroptosis is a newly identified form of nonapoptotic programmed cell death characterized by iron-dependent accumulation of lipid peroxides, and has drawn wide attention since the term was put forward in 2012 [25]