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doi: 10.1016/j.intimp.2012.01.015 102

Such changes in turn leads to weakened SCN output, impaired photic entrainment, and loss of temporal coherence across organ systems

Overtreatment may result in craniosynostosis in infants who have not undergone complete closure of the fontanelles, and in premature closure of the epiphyses in pediatric patients still experiencing growth with resultant compromised adult height
