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However, MDSCs often suppress the immune response and cause tumour escape (140, 141)
This could be due to a Zn-induced inhibition of phosphatase activity, leading to Mitogen-activated protein kinase (MAPK) and activator protein-1 (AP-1) activation, resulting in the enhanced IL-8 expression [140]
For Ent2, the total number of Abp1+ sites is lower than those observed for Ent1 indicating its less frequent presence (Fig
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