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Description
130 SinghakumarR.BoontemP.EkthuwapraneeK.SotthibundhuA.MukdaS.ChetsawangB.et al (2015)
The mtDNA is more vulnerable to excessive ROS-related damage to biomolecules, such as DNA repair enzyme proteins, than nuclear DNA (112), which disrupts the ETC and ultimately induces dysregulation of mitochondrial OXPHOS (113)
In another clinical trial, 66 patients with stage IIIB non-small cell lung cancer were randomized to receive pentoxifylline (400 mg, three times daily) and alpha-tocopherol (300 mg twice daily) plus radiation or radiation alone
